Organizations often have more than one manufacturing site, and each location might have its own specific strengths. For example, a manufacturing facility with low-cost, well-trained talent may have less capital equipment costs. This manufacturing line will be more labor-intensive. Conversely, the company may have manufacturing sites where the labor cost is too high for the product, necessitating a more automated approach to production. From my experience, large organizations often have both strengths, just not in a single manufacturing line.
Which line to go with is typically defined at the start of a product development project. But, what happens when demand changes?